Localisation of foreign bodies in the eye.

manner in which cocain can be used as a test for paralysis of the sympathetic nerve, as a valuable quality. Information with regard to other drugs in this respect would be valuable. It has been suggested to me that the stimulating action on the sympathetic nerve might prove to be a test of the power of a drug to act as a stimulant of the central nervous system, and that so it might beconme a test of the liability of a drug to become a drug of addiction, a valuable test should it be substantiated. My own experience of cocain substitutes is as follows: I have already expressed my opinion of novocain for infiltration; but have not tised it for instillation. I have found holocain in 2 per cent. solution satisfactoryT for superficial anaestlhesia by instillation, but it causes distinctly more smarting than cocain of similar strength; I have not used it for intraocular operations. I have used 2 per cent. and 4 per cent. stovain by instillation both for superficial atnaesthesia and for cataract operations, it is more irritating than cocain, it gives a satisfactory superficial anaesthesia, but I have thought it unsatisfactory for cataract operations, and on two occasions have lhad to complete the operation with thie aid of cocain. I hlave used butyn a few times in the form of gelatin lamellae and 2 per cent. drops for superficial anaesthesia only, the -anaesthesia seemed satisfactory but smarting was rather marked. I know, of no certain case of addiction to any of these drugs as a result of their clinical use bv my,self or others, the most I can say of one case is that I suspect the cocain habit was contracted as a resuilt of the tuse of cocain ointment for a fistula-in-ano.